Adult Asthma

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Asthma Quality of Life Questionnaire (AQLQ)
Standardised Asthma Quality of Life Questionnaire (AQLQ(S))
Mini Asthma Quality of Life Questionnaire (MiniAQLQ)
Acute Asthma Quality of Life Questionnaire (Acute AQLQ)
Asthma Control Questionnaire (ACQ)
Contact: Professor Elizabeth Juniper

Asthma Quality of Life Questionnaire (AQLQ)

Overview

Five independent studies have demonstrated the strong evaluative and discriminative measurement properties and validity of the Asthma Quality of Life Questionnaire. It has been used successfully in a large number of clinical trials and in clinical practice around the world.

References

1. Juniper EF, Guyatt GH, Epstein RS, Ferrie PJ, Jaeschke R, Hiller TK. Evaluation of impairment of health related quality of life in asthma: development of a questionnaire for use in clinical trials. Thorax 1992; 47: 76-83.
2. Juniper EF, Guyatt GH, Ferrie PJ, Griffith LE. Measuring quality of life in asthma. Am Rev Respir Dis 1993; 147: 832-838.
3. Juniper EF, Guyatt GH, Willan A, Griffith LE. Determining a minimal important change in a disease-specific quality of life questionnaire. J Clin Epidemiol 1994; 47: 81-7.
4. Rowe BH, Oxman AD. Performance of an asthma quality of life questionnaire in an outpatient setting. Am Rev Respir Dis 1993; 148: 675-81.
5. Rutten-van Molken MPMH, Clusters F, Van Doorslaer EKA, Jansen CCM, Heurman L, Maesen FPV, Smeets JJ, Bommer AM, Raaijmakers JAM. Comparison of performance of four instruments in evaluating the effects of salmeterol on asthma quality of life. Eur Respir J 1995; 8: 888-98.
6. Juniper EF, Johnston PR, Borkhoff CM, Guyatt GH, Boulet LP, Haukioja A. Quality of life in asthma clinical trials: comparison of salmeterol and salbutamol. Am J Respir Crit Care Med 1995; 151: 66-70.
7. Leidy NK, Coughlin C. Psychometric performance of the Asthma Quality of Life Questionnaire in a US sample. Quality of Life Research 1998; 7: 127-134.
8. Sanjuas C, Alonso J, Sanchis J, Casan P, Broquetas JM, Ferrie PJ, Juniper EF, Anto JM. The quality of life questionnaire with asthma patients; the Spanish version of the Asthma Quality of Life Questionnaire. Archivos de Bronconeumologia 1995; 31: 219-226.
9. Apter AJ, Reisine ST, Affleck G, Barrows E, ZuWallack RL. The influence of demographic and socioeconomic factors on health-related quality of life in asthma. J Allergy Clin Immunol 1999; 103:
10. Caro JJ, Caro I, Caro J, Wouters F, Juniper EF.  Does Electronic implementation of questionnaires used in asthma responses compared to paper implementation.  Qual Life Res 2001; 10: 683-691
11. Juniper EF, Norman GR, Cox FM, Roberts JN.  Comparison of the standard gamble, rating scale, AQLQ and SF-36 for measuring quality in asthma.  Eur Respir J 2001; 18: 38-44. 

Original Language

Translations

Formats

• Interviewer-administered
• Self-administered 

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Standardised Asthma Quality of Life Questionnaire (AQLQ(S))

Overview

However, in long-term studies, patients' activities change and the patient-specific approach may not be appropriate. Therefore, we have developed 5 "standardised" activities to replace the patient-specific ones in the AQLQ. The new instrument has been fully validated. Reliability and cross-sectional validity are almost identical to the original AQLQ. Responsiveness and longitudinal validity are still excellent but not quite so good as the original instrument.

References

1. Juniper EF, Buist AS, Cox FM, Ferrie PJ, King DR. Validation of a standardized version of the Asthma Quality of Life Questionnaire. Chest 1999; 115: 1265-1270

Original Language

Translations

Formats

• Interviewer-administered
• Self-administered

Standardised Asthma Quality of Life Questionnaire for 12 years and Older

Some clinical trials in adults are now required to include children 12 years and older.  We have made minor modification to the original AQLQ(S) so that all the questions can be answered by younger patients (e.g. the question concerning impairment of work-related activities now asks about work/school-related activities).  Although the problems that bother children with asthma are fairly similar to those that bother adults, they are not identical.  Children are certainly bothered by the same symptoms, activity limitations and fears but they are also bothered by feeling different from their peers.  In addition, children do not specifically identify environmental triggers as being troublesome, it is usally the activities that these triggers limit that are identified as being troublesome.  There has been no formal validation study of the 'AQLQ(S) 12 years and older' but initial data from clinical trials suggest that there are no problems with validity.

We do not include this questionnaire in the AQLQ package but it is available if needed.  Ideally quality of life in children 12-17 years should be assessed using the Paediatric Asthma Quality of Life Questeionnaire.

Translations

Afrikaans Belgian French Bulgarian Cantonese Chinese for Hong Kong  Chinese (Mandarin) Chinese (Malaysia) Chinese (Singapore) Chinese (Taiwan) Czech Danish Dutch for Belgium Dutch for Netherlands English for Australia English for Canada English for Hong Kong  English for South Africa English for U.K. Filipino Finnish Flemish French

German Greek Hebrew  Hindi Hungarian Indonesian  Italian Korean Malay for Malaysia Norwegian Polish Portuguese Quebec French Russian  Spanish Spanish for North America Swedish Thai Turkish Vietnamese

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Mini Asthma Quality of Life Questionnaire (MiniAQLQ)

Overview

References

1. Juniper EF, Guyatt GH, Cox FM, Ferrie PJ, King DR. Development and validation of the Mini Asthma Quality of Life Questionnaire. Eur Respir J 1999; 14: 32-38

Original Language

Translations

Formats

• Self-administered

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Acute AQLQ Package

Overview

When patients have an acute severe exacerbation of their asthma, not only are they troubled by their symptoms, the experience can also be emotionally distressing.  The AQLQ, the AQLQ(S) and the MiniAQLQ focus on the things that are troublesome to asthma patients during their day-to-day lives in the community and they ask patients to recall their experiences during the previous weeks.  Therefore, they are not suitable for capturing the rapidly changing experiences that occur during acute severe asthma.  We have modified the AQLQ to focus on the problems that are distressing to patients when they experience acute severe asthma that requires treatment in hospital and which can be expected to respond within hours to therapy.  The Acute AQLQ has been fully validated.

Reference:

1. Juniper EF, Svensson K, Mork A-C, Stahl E. Measuring health-related quality of life in adults during an acute asthma exacerbation.  Chest (November 2003 in press)

Original Language

English for the UK and North America

Translations

French for Canada

Thai

Formats

Interviewer administered

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Adult AQLQ Package

Package Content

• Asthma Quality of Life Questionnaire (Interviewer-administered)
• 4 coloured response option cards
• Asthma Quality of Life Questionnaire (Self-administered)
• Standardised Asthma Quality of Life Questionnaire (Interviewer-administered)
• Standardised Asthma Quality of Life Questionnaire (Self-administered)
• Mini Asthma Quality of Life Questionnaire (Self-administered)
• Acute Asthma Quality of Life Questionnaire (interviewer administered)
• Background Information and Interviewing Tips (an implementation manual)
• Reprints of published manuscripts describing the development, validation and interpretation of the AQLQ, AQLQ(S), MiniAQLQ

Package Availability

There is a user fee for commercial organisations who have not supported our research program.

Package Ordering

Contact Professor Elizabeth Juniper to order your package. Please be sure to include your full mailing address and specify the language you require.

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Asthma Control Questionnaire (ACQ)

Overview

International guidelines indicate that the primary goal of asthma treatment is to achieve optimum control (minimisation of day and night time symptoms, activity limitation, bronchoconstriction and short-acting bronchodilator use) and thus reduce the risk of life-threatening exacerbations and long-term morbidity.  The 7-item Asthma Control Questionnaire has been developed and validated to measure the adequacy of asthma control as defined by the international guidelines.

References

1. Juniper EF, O'Byrne PM, Guyatt GH, Ferrie PJ, King DR. Development and validation of a questionnaire to measure asthma control. Eur Respir J 1999; 14: 902-907.
2. Juniper EF, O'Byrne PM, Roberts JN.  Measuring asthma control in group studies: do we need airway calibre and rescue ß²-agonist use? Respiratory Medicine 2001; 95: 319-323.

Original Language

English for North America

Translations

Afrikaan Australian English Austrian German  Bulgarian Cantonese for Hong Kong  Chinese for Mandarin Chinese for Taiwan Chinese for Singapore Croatian  Czech Danish Dutch English for Hong Kong English for New Zealand English for Philipines English for South Africa English for Singapore English for UK Estonian Finnish Filipino  Flemish French French for Québec German Greek Hebrew Hindi

Hungarian   Indonesian  Italian Japanese  Korean Latvian Lithuanian Malay Mandarin Chinese for Malaysia  Norwegian Polish Portuguese for Brazil Portuguese Romanian  Russian Spanish Spanish for Argentina Spanish for Chile Spanish for Colombia  Spanish for Costa Rica Spanish for Mexico Spanish for North America Spanish for Peru  Swedish Swedish for Finland Thai Urdu for Pakistan  Vietnamese

Formats

Self-administered

Asthma Control Diary (ACD)

Overview

It has often been assumed that more accurate and precise data may be obtained in asthma clinical trials if patients complete daily diaries than if they are asked to recall their experiences during a clinic visit.  As a result, patients participating in asthma clinical trials are often required to complete diaries and make recordings of PEF.  For the Asthma Control Diary, we have modified the Asthma Control Questionnaire for daily completion using PEF instead of FEV1.   However, although the Asthma Control Diary has strong measurement properties, they are not as good as those of the Asthma Control Questionnaire.  The study cited below shows that it is quicker, more accurate and much easier to obtain asthma control data with the questionnaire than the diary.

Reference:

1. Juniper EF, O'Byrne PM, Ferrie PJ, Kingt DR, Roberts JN.  Measuring asthma control: clinical questionnaire or daily diary? Am J Respir Crit Care Med 2000; 162: 1330-1334.

Original Language:

North American English

Asthma Control Questionnaire Package:

Package Content

• Asthma Control Questionnaire
• Asthma Control Diary
• Reprints of published manuscripts describing the development, validation and comparison of these two instruments.

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Contact Details

Health-Related Quality of Life

CE&B